NUCLEUS TRACTUS SOLITARII: INTEGRATING STRUCTURES
نویسندگان
چکیده
منابع مشابه
Hemodynamic effects elicited by stimulation of the nucleus tractus solitarii.
Microinjection of the excitatory amino acid L-glutamate into the nucleus tractus solitarii (NTS) elicits decreases in arterial pressure and heart rate. In the present study, we sought to determine the regional hemodynamic effects that were correlated with changes in arterial pressure and heart rate produced by stimulation of the NTS. In anesthetized rats, blood flow in the renal (RBF), superior...
متن کاملCardiac damage after lesions of the nucleus tractus solitarii.
Humans with central lesions that augment sympathetic nerve activity are predisposed to cardiac arrhythmias, myocardial lesions, and sudden death. Previously, we showed that selectively killing neurons with neurokinin-1 receptors in the nucleus tractus solitarii (NTS) of rats attenuated the baroreflex and, in some animals, led to sudden unexplained death within approximately 2 wk. Interruption o...
متن کاملFrequency limits on aortic baroreceptor input to nucleus tractus solitarii.
The frequency of baroreceptor volleys to the central nervous system can influence the fidelity of baroreceptor signal transmission and thus may affect baroreflex regulation of blood pressure. We examined 1) the extent to which frequency-dependent depression of aortic baroreceptor signals was initiated at the first central synapse between primary baroreceptor fibers and second-order nucleus trac...
متن کاملHypoxia activates nucleus tractus solitarii neurons projecting to the paraventricular nucleus of the hypothalamus.
Peripheral chemoreceptor afferent information is sent to the nucleus tractus solitarii (nTS), integrated, and relayed to other brain regions to alter cardiorespiratory function. The nTS projects to the hypothalamic paraventricular nucleus (PVN), but activation and phenotype of these projections during chemoreflex stimulation is unknown. We hypothesized that activation of PVN-projecting nTS neur...
متن کاملIL-6 microinjected in the nucleus tractus solitarii attenuates cardiac baroreceptor reflex function in rats.
Recent gene array and molecular studies have suggested that an abnormal gene expression profile of interleukin-6 (IL-6) in the nucleus tractus solitarii (NTS), a pivotal region for regulating arterial pressure, may be related to the development of neurogenic hypertension. However, the precise functional role of IL-6 in the NTS remains unknown. In the present study, we have tested whether IL-6 a...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 1999
ISSN: 0958-0670
DOI: 10.1017/s0958067099019120